David G. Nathan Professor of Pediatrics, Harvard Medical School
Chairman, Pediatric Oncology, Dana-Farber Cancer Institute
Investigator, Pediatrics, Boston Children’s Hospital
Dr. Stuart H Orkin serves as Chairman of the Department of Pediatric Oncology at DFCI, the David G. Nathan Professor of Pediatrics at Harvard Medical School, and an Investigator of the Howard Hughes Medical Institute. In addition, he is a principal faculty member of the Harvard Stem Cell Institute (HSCI) and an associate of the Broad Institute of MIT/Harvard. He received his BS from MIT and MD from Harvard Medical School. He completed pediatric hematology/oncology training at Boston Children’s Hospital and the Dana Farber Cancer Institute (DFCI), and trained in the laboratory of Philip Leder at NIH. His research focuses on intersections of transcriptional control with stem cell biology, hematopoiesis, and cancer. His research achievements include comprehensive dissection of the molecular basis of the thalassemia syndromes, positional cloning of the first human disease gene, cloning of the first master regulator of blood cell development, and identification of a major silencer of fetal hemoglobin expression.
Dr. Orkin served on the National Research Council Committee on Mapping the Human Genome and as co-chair (with Arno Motulsky) of the Panel to Assess the NIH Investment in Gene Therapy. He was the inaugural chair of the Grants Reviews Committee of the California Institute of Regenerative Medicine (CIRM).
He is also an elected member of the National Academy of Sciences (NAS), Institute of Medicine, and American Academy of Arts and Sciences, and recipient of the E. Mead Johnson Award of the American Academy of Pediatrics, the Warren Alpert Prize, the Helmut Horten Foundation Prize (with Sir David Weatherall and YW Kan), the Distinguished Research Award from the Association of American Medical Colleges (AAMC), the E. Donnall Thomas, Dameshek and Basic Science Mentor Awards of the American Society of Hematology (ASH), and the Metcalf Award of the International Society of Experimental Hematology (ISEH). In 2013 he received Jessie Stevenson Kovalenko Medal of the NAS for “important contributions to the medical sciences”. In 2014 he was recognized by the William A. Allan Award of the American Society of Human Genetics, and will receive the Karl Landsteiner Memorial Award from the American Association of Blood Banks in 2016.